first of all, welcome to genvibemy gas mileage always drops in the winter. Hard to know if the drop you are seeing is normal, or a sign of something needing maintenance. Also. keep in mind that one tank of gas taken individually is not a good indication, becuase it depends a lot on how full you filled up, which will vary each time no matter how careful and methodical you are. The mass air flow (MAF) sensor monitors how much air is passing though the air intake, affects fuel/air mixture, and can have an effect on fuel economy. THey are not cheap though, so some care iis needed when cleaning them.The fuel injector cleaner is really easy, and not that expensive, so that's a good thing to try. As others have already said, the spark plugs, if original, probably need to be replaced. There are no spark plug wires to replace, so if you take it to someone to have the plugs replaced, don't let them tell you they replaced the plug wires. And too low tire pressure can kill mpgs, as can poor alignment.
viewtopic.php?f=17&t=6088&#p65128 has an excerpt from a factory service manual on what to check if fuel economy is low, many of the things there are involved. Definitely start with the easy stuff first, and since this is your first winter with the car, it's really hard to know if the drop is typical winter drop or a sign of some repairable problem.If you do not have a copy of the owner's manual, you can download a PDF of it from
http://forums.genvibe.com/zerothread?id=1010 In the 2005 Vibe owners manual there, page 5-12 has a picture of the engine compartment. In that picture, "A" is the windshield washer tank, "E" is the coolant overflow tank. Let us know which of those has the purple stuff in it.